Submissions to the IBC

The review process

All Institutional Biosafety Committee protocols will undergo administrative pre-review by IBC office staff for completeness and clarity. If the IBC office finds significant issues with your submission, you will have the chance to resolve those issues before your protocol is assigned to a reviewer.

Based on the information in your protocol, the IBC office will determine which type of review your protocol will receive, full committee review or expedited review.

Full committee review

Full committee review is required for all non-exempt research. Non-exempt research is any research that falls under sections III-A through III-E of the NIH Guidelines. When you submit a protocol that involves non-exempt research, the IBC office will add it to the agenda of an IBC meeting and assign reviewers. Protocols must be received two weeks prior to an IBC meeting to be considered for review that month.

See upcoming meetings and deadlines
Full committee review process

Expedited review

Expedited review is required for all exempt research or teaching activity. Exempt research includes research that falls under section III-F of the NIH Guidelines, any research or teaching activities that involve Biosafety Level 2 or higher biological materials, or teaching activities that involve rDNA or synthetic nucleic acid molecules regardless of biosafety level. When you submit a protocol that involves exempt research or teaching activities, the IBC office and the Environmental Health and Safety - Biological Safety Program will review the work.

Expedited review process

Avoid protocol noncompliance

Be sure to follow the terms and conditions of your approved protocol. Noncompliance can lead to temporary or permanent suspension of the activity, more frequent laboratory inspections or monitoring, additional training of personnel, removal of personnel or animals from the protocol, or suspension of funding.

Examples of noncompliance include, but are not limited to:

  • beginning research projects without IBC approval
  • unlisted personnel involved in a protocol
  • failure to complete required training
  • use of unapproved biological materials
  • conducting unapproved procedures
  • working in an unapproved research location
  • improperly disposing of biological materials

Protocol deviations, noncompliance, and other situations that may impact subject safety, confidentiality, information security, privacy, etc., are known as reportable events.

Learn more about reportable events

Biosafety Policies & Guidelines

View the Biosafety Policies & Guidelines

Find out more about how to comply with NIH, CDC, OSHA, and other applicable biosafety regulations.

View the Indiana University Biosafety Manual