August 29, 2017

INSIDE THIS ISSUE

  • Feature Story
  • Announcements
  • Center Spotlight
  • Faculty Spotlight
  • Student Spotlight
  • Translational Research Impact
  • OVCR Internal Grant Deadlines
  • OVCR Events and Workshops
  • Other Events and Workshops
  • Recent External Funding Awards
  • Current External Funding Opportunities
FEATURE STORY

Doctor gets grants to protect troops from mosquito-borne viruses
Image of the Molly Duman Scheel, PhD
Molly Duman Scheel, PhD
Molly Duman Scheel, PhD, associate professor of medical and molecular genetics at Indiana University School of Medicine-South Bend, was awarded two multi-year grants from the Department of Defense (DOD) to aid her work in combating mosquito-borne illnesses and keep field troops safe from diseases, such as Zika and dengue.

Dr. Scheel received a $1.1 million, three-year Investigator Initiated Research award from DOD to address mosquito proliferation through larvicides. She shares the grant with University of Notre Dame research associate professor Nicole Achee of the Department of Biological Sciences.

Dr. Scheel received $750,000 from the Deployed War Fighter Protection (DWFP) Program to address adult mosquito abatement. Partners on the project include David Severson of Notre Dame, the Walter Reed Army Institute of Research in Maryland and the Armed Forces Research Institute of Medicine Sciences in Thailand.

The Scheel lab, in conjunction with Notre Dame’s Eck Institute for Global Health, has developed a larvicide based on interfering RNA pesticides, a novel class of environmentally safe insecticides. The effectiveness of the larvicide has been proven in the lab and is being tested in a tropical testing ground in Belize managed by Notre Dame. The larvicide is applied to naturally developing pockets of standing water that turn up in barrels, abandoned tires and other receptacles.

For the grant with Dr. Achee, Dr. Scheel will introduce ovitraps, or traps designed to be attractive environments for mosquitoes to lay eggs. While the concept of ovitraps has been developed and tested, Scheel’s project will introduce new larvicides that are environmentally safe and to which mosquitoes have not developed resistance. Besides Scheel and Achee, the research team will include Notre Dame researchers John Grieco, Dave Severson and Na Wei, of the Eck Center, as well as Kathleen Eggleson, a researcher at IU School of Medicine-South Bend.

For the DWFP-funded study, Scheel, Severson and their military collaborators will extend their interfering RNA larvicide work to identify pesticides that target both developing as well adult mosquitoes. Adult mosquitoes, which feed on plant nectar, require sugar meals for survival. In recent years, attractive toxic sugar baits have demonstrated great potential in the war against mosquitoes. The use of interfering RNA pesticides, a biorational alternative to conventional pesticides, would reduce the impacts of these toxic baits on non-target insects.

"The interest the Department of Defense has in this project acknowledges the large number of military personnel, military support personnel and military family members who are deployed to areas where mosquito-borne illnesses are prevalent,” Dr. Scheel said. “Their exposure to Zika and dengue fever is ongoing. In the case of Zika, a troop’s potential to infect a spouse or partner is another level of concern."

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ANNOUNCEMENTS

IUPUI Research On-Boarding Orientation Coming
Image of the IUPUI Research On-Boarding Orientation
IUPUI Research On-Boarding Orientation
Target Audience: All IUPUI faculty, with a special emphasis on new and junior faculty
When: Tuesday, October 24, 2017 | 9:00 am – 2:00 pm
Where: : IUPUI Campus Center

The Office of the Vice Chancellor for Research is pleased to host the IUPUI Research On-Boarding Orientation (ROBO) program. Participants will:
  • Gain a better understanding of the IUPUI campus level research organizational structure
  • Learn about many programs and services that are available to help faculty succeed in their research and creative activities
  • Receive insights from current faculty about how they were able to achieve early success
  • Connect with resources that are available through centers, institutes, and other research support units on campus
  • Meet new research colleagues and possibly explore potential collaborations
ROBO is a comprehensive day-long event beginning with a morning session (9:00am - 11:50am) that will include an overview of all three major campus level research offices. Short presentations will be given by staff from the Office of Research Development, Office of Research Administration, and Office for Research Compliance.

Broad disciplinary roundtable discussions will be held for new and junior faculty in particular, and lunch will be provided (12:00pm - 1:00pm). These roundtable discussions are designed to be casual conversations facilitated by current faculty who have experienced early success in their careers here at IUPUI.

In addition, a resource fair for all interested will be held in the afternoon from 12:00pm to 2:00pm. This will be an excellent opportunity to engage with and gather information from center, institute, and campus unit representatives about resources, support and opportunities that can help advance faculty research programs. Getting to know what types of activities are happening in centers and institutes is a great way to make valuable connections with fellow researchers and perhaps spark interest in potential research collaborations with faculty at all ranks and across many disciplines, which is an important strategic focus for IUPUI.

Click here to register

Questions can be directed to Alicia Gahimer (algahime@iupui.edu or 317-278-0249) or Etta Ward (emward@iupui.edu or 317-278-8427).

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IUPUI and Johns Hopkins University present: 'Progress in Scaffold-Free Biofabrication'
Image of the Regenova
Regenova
We are pleased to invite you to the IUPUI-JHU Symposium 'Progress in Scaffold-Free Biofabrication' and to our 2nd Annual 3D Bioprinting Core Open House. This event will feature both the 'Regenova Bio 3D-Printer' by Cyfuse Biomedical and the IncuCyte ZOOM automatic fluorescent microscopy platform.

This year, our Symposium will be sponsored by the Regenova's producer Cyfuse Biomedical, KK and by its US distributor Amuza Inc. We are also honored by the participation of national (Johns Hopkins, Brown, Pittsburg and other Universities) and international (Japan, Russia etc.) teams.

Click here to read more about this story

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SEIRI Seed Grants
Image of the Dr. Pratibha Varma-Nelson
Dr. Pratibha Varma-Nelson, SEIRI Executive Director
The STEM Education Innovation and Research Institute (SEIRI) recently awarded seven projects a total of $210,000 as part of the SEIRI Seed Grant program. Pratibha Varma-Nelson said, "The grants provide faculty within STEM departments seed funding for education, innovation and research. They will also enable faculty to be more competitive to receive external funding, such as for the National Science Foundation of National Institutes of Health."

Congratulations to the IUPUI researches across several STEM disciplines who submitted high-quality projects for the SEIRI Seed Grant program.

Click here to read more about this story

To learn more about the projects, see recent press release at https://news.iu.edu/stories/2017/08/iupui/releases/10-seiri-seed-grant-projects.html

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IUPUI Translating Research Into Practice Showcase – November 1
All are welcome to attend the IUPUI Translating Research Into Practice Showcase on Wednesday, November 1, 5:00 pm - 6:30 pm, in the Campus Center. Dr. Mark Kelley, the 2017 Bantz-Petronio Translating Research Scholarship Into Practice Award recipient will share information about his exciting work that exploits basic science discovery in cancer and other diseases for targeted therapy.

In addition, several of IUPUI's distinguished faculty scholars will showcase their translational research and illustrate how they improve people's lives at the IUPUI TRIP Community Showcase in the IUPUI Campus Center. These scholars have partnered with community members and other to translate their research into viable practices that improve our communities.

Participants at the showcase will have a chance to talk directly with our researchers to learn more about their work and to discover new possibilities for solving problems in our communities.

All students, faculty, staff and community partners are invited to attend this no cost event.

Click here to register

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New Residency Program Helps Create More Welcoming Campus
The IUPUI Arts and Humanities Institute (IAHI) will host two artists-in-residence during 2018. Residents will be provided an honorarium ($3000), a materials and installation budget ($8500), housing, and round trip airfare.

Residents will be responsible for developing a public artwork for the IUPUI campus during their residency. They will develop this work in consultation with the IAHI director and advisory team. During their residency, they will be responsible for 3-4 hours of studio visits at the Herron School of Art and Design and participate in two IAHI public programs (e.g. panel discussion). Depending on the nature of the work, artworks may not be complete during the residency. In this case, residents may need to return to IUPUI for its installation.

The IAHI recognizes that public art practice takes many forms and encourages applicants to pursue a wide variety of approaches.

The IAHI Welcoming Campus Residencies are funded by the IUPUI Welcoming Campus Fund, the School of Engineering and Technology, and the Office of the Vice President for Research. They are offered in collaboration with the City State residency program. City State is a collaboration of Central State Mansion, the IAHI, Ignition Arts, iMOCA, People for Urban Progress, and PRINTtEXT.

Applications are due on October 15, 2017

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Subrecipient Invoice Checklist
The Office of Research Administration (ORA) has a new tool to assist departments while performing an invoice review for a subrecipient of a federal or federal pass-through award. The Subrecipient Invoice Checklist is a one page document that lists the review criteria for the Fiscal Officer and Principal Investigator as explained in the Subrecipient Monitoring Post Award Procedure Guide.

Uniform Guidance requires Indiana University perform subrecipient monitoring on federal and federal pass-through subawards to ensure that all expenditures are in compliance with Federal regulations and in accordance with the requirements of the subaward.

Fiscal Officers and Principal Investigators are responsible for subrecipient costs charged to the grant. The Subrecipient Invoice Checklist will facilitate the review process and also provide assurance that subrecipient monitoring requirements are met. ORA recommends that departments use the Subrecipient Invoice Checklist as a Best Practice for all subrecipients. In the event of an audit, the more boxes that have been checked on the Subrecipient Invoice Checklist, the less risk for audit findings.

The Subrecipient Invoice Checklist should be uploaded with the subrecipient invoice or saved in the notes and attachments panel of the KFS payment request document.

Links to the Subrecipient Invoice Checklist, IU Policy and Uniform Guidance can be found on the ORA website at: http://www.researchadmin.iu.edu/GrantContract/gc-gfo/gfo_sub_monitoring.html

Please contact Paula Maloian at pmaloian@iu.edu with questions.

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CENTER SPOTLIGHT

Recording the past and the future in 3-D
Image of the Jenny Johnson demonstrates the use of a mobile Creaform 3-D scanner
Jenny Johnson demonstrates the use of a mobile Creaform 3-D scanner.
The handheld scanner looks like an old-school video game controller, a clunky throwback to the early days of Atari. But these mobile 3-D scanners used by the staff in the Indiana University-Purdue University Indianapolis University Library Center for Digital Scholarship are actually very advanced technology, and they are changing the way we record recent history, ancient history and even the future.

"About two years ago, we decided to explore 3-D technology and what scanning could look like," said Jenny Johnson, head of digitization services for the Center for Digital Scholarship. "Every community and cultural heritage institution that we work with has 3-D objects. As the technology has gotten better, computer processing has gotten better, and because costs have been reduced a little bit with the technology, we decided to dive into the specifics and see what we could do. The Benjamin Harrison team was really interested in this, and they've got an eCollection initiative to document more of their items."

Click here to read more about this story

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FACULTY SPOTLIGHT

Professor named Distinguished Scholar by the National Communication Association
Image of the Sandra Petronio, Ph.D.
Sandra Petronio, Ph.D.
The National Communication Association has recognized Sandra Petronio, a professor in the Department of Communication Studies in the School of Liberal Arts at Indiana University-Purdue University Indianapolis, with the Distinguished Scholar Award.

Given annually, the National Communication Association Distinguished Scholar Award is the association's highest accolade, honoring a lifetime of scholarly achievement in the study of human communication. Recipients are selected by their peers to showcase the best of the communication discipline.

Petronio, who has more than three decades of scholarly work with wide influence in the communication discipline and beyond, is the first such honoree from IUPUI. Indiana University Bloomington professors Robert Ivie (2013), John Louis Lucaites (2012) and James Andrews (2000) are among some 100 previous recipients of the award since its inception in 1992.

"Learning that I was selected to receive this prestigious honor is exciting and even a bit overwhelming, but most of all rewarding," said Petronio, who also teaches in the IU School of Medicine and the Charles Warren Fairbanks Center for Medical Ethics at IU Health and has had appointments at the IU schools of informatics and nursing. "I've been proud of the work we've been able to do at IUPUI in the field of communication, and to be recognized nationally is a highlight of my career."

Petronio is best known for Communication Privacy Management, or CPM, theory, a scientifically grounded theory to understand the central motivations, goals, rules and outcomes of privacy management. There have been more than 5,000 citations since 2012 on Google Scholar and more than 740 articles engaging the theory. Petronio and her colleagues continue to develop evidence of consistencies and distinct patterns of privacy management emerging across cultures and contexts, suggesting the opportunity to develop a general theory. CPM has a global reach and has been applied in a wide variety of contexts including health, education, family, business, social media, religion, security and interpersonal relationships.

She has also been an important voice in the communication field, arguing for the importance of translational scholarship and modeling that work. In 2007, Petronio spearheaded the IUPUI Center for Translating Research into Practice and most recently launched the Communication Privacy Management Center at IUPUI.

"The communication discipline has a long tradition of exceptional scholarship," NCA Executive Director Paaige Turner said. "We're proud to recognize Dr. Petronio's contributions with this well-deserved award."

Petronio will receive her award during the NCA's 103rd annual convention, taking place Nov. 16-19 in Dallas, Texas.

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STUDENT SPOTLIGHT

From Project SEED to Capitol Hill
Image of the Dana K. Oakes and Sen. Joe Donnelly
Dana K. Oakes and Sen. Joe Donnelly
Senior biology-neuroscience double major Dana K. Oakes began independent, faculty-mentored research on retinal development using human pluripotent stem cells in the laboratory of Dr. Jason Meyer in the Department of Biology, Purdue School of Science at IUPUI, through Project SEED in summer 2013. Since then she has been involved with research continuously, including in the Biology Freshman Work Program. With funding through the Life-Health Sciences Institute and the IUPUI Center for Research and Learning’s (CRL) Undergraduate Research Opportunities Program (UROP), she has been working in the laboratory of Dr. Imranul Alam in the Division of Endocrinology, Indiana University School of Medicine. In fall 2016, she presented to the American Society for Bone and Mineral Research on autosomal dominant osteopetrosis type II, a rare bone-density disease, for which Dr. Alam’s was the first laboratory in the world to develop a mouse model. With her UROP grant, Dana studied a potential drug target for glucocorticoid-induced osteoporosis, the most common form, garnering CRL’s 2017 Bowling-Jones-Russo Memorial Undergraduate Research Award.

At the fall 2016 UROP orientation session, CRL interim executive director Dr. Dominique M. Galli announced the call for proposals for the Council on Undergraduate Research’s (CUR) annual Posters on the Hill symposium in Washington, D.C. http://www.cur.org/conferences_and_events/student_events/posters_on_the_hill_2017/ Dana reflects, “There are all these things I’ve gotten to do because of CRL!” At Dr. Alam’s urging, she submitted two abstracts to CUR, and he mentored her in shaping them for a broader audience. During the two-day conference, she discussed her research with Senators Todd Young and Joe Donnelly, as well as with representatives from the offices of Congresswoman Susan W. Brooks and Congressman André Carson. Dana also spoke with interns, who tended to be a little older than the students, and with other health-sciences poster presenters.

Image of the Dana K. Oakes and Sen. Todd Young
Dana K. Oakes and Sen. Todd Young
The most thought-provoking question she received during Posters on the Hill actually came from an age-peer intern with a political-science background: "Why is funding from NIH (National Institutes of Health) important? How does that affect you?” Dana explained that such federal funding allows labs to do research and makes places for students to learn hands-on, to translate research to real-world, data-driven solutions. Although she was a bit nervous about being by herself in our nation’s capital and about meeting the senators, overall, it was a relaxed environment. "I had a good time. I learned a lot," she recalls, adding, "I learned more about myself than I thought I would. I learned that civic engagement is more important that I’d thought." An aspiring physician-scientist, Oakes relates, "I visited the NIH clinical center and fell in love with it." As a result, "I applied to medical schools in the D.C. area." Asked whether she would recommend Posters on the Hill to others, she replied, "Absolutely! And not just science students." Gratefully, she acknowledged, "I wouldn’t have been able to go without CRL’s help."

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TRANSLATIONAL RESEARCH IMPACT

IU-based pediatric patient care IT startup chosen for prestigious national business program
Image of the Dana K. Oakes and Sen. Joe Donnelly
Dr. Stephen Downs
A health care technology startup based on software developed at the Indiana University School of Medicine is moving closer to fulfilling its plan to improve pediatric patient care across the country.

Digital Health Solutions LLC commercializes software called Child Health Improvement through Computer Automation, or CHICA, to help physicians identify pediatric patients' problems earlier and better document the quality of care. The end result is earlier detection and treatment of problems -- and better health outcomes for children.

"When a family arrives, they receive an electronic tablet that asks 20 questions. The family provides information on a wide range of topics, including general preventive counseling, asthma, attention deficit hyperactivity disorder, autism, domestic violence and more," he said. "Based on the family's responses, CHICA uses its prioritization process to select the most important issues for the physician to address during the visit."

Digital Health Solutions has been selected to participate in an intensive 12-week program organized by Louisville-based startup accelerator XLerateHealth. Digital Health Solutions and seven other early-stage health care companies will meet with mentors and health and wellness companies Aug. 9 through Oct. 27. The program includes one-on-one sessions with mentors, classroom time and focused customer discovery.

Image of the Dana K. Oakes and Sen. Joe Donnelly
Tammy Dugan
Downs and Tammy Dugan, chief technology officer, will represent the company during the program, including a three-day session Aug. 9-11.

"After that, a member of each participating company attends meetings every Friday, through and including Oct. 20," Downs said. "The participants attend the entire week of Oct. 23, which includes a 'Demo Day' when they pitch their business to investors and health care providers. The program focuses on the business skills and activities that are unique to startups."

Dugan said there are several benefits to participating in the XLerateHealth program.

"We want Digital Health Solutions to provide a product that will benefit pediatric patients, their families and our customers," she said. "The program provides us the opportunity to connect with other health care tech startups and health systems to pursue strategic partnerships."

Dugan said being selected to join the XLerateHealth program is exciting, especially because of the people involved.

"Co-founders Jackie Willmot and Bob Saunders have so much experience and expertise in the health technology arena, and Louisville is a great ecosystem for health tech startups," she said. "Steve and I feel privileged to be part of this fifth cohort of companies participating in the program."



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OVCR INTERNAL GRANT DEADLINES

Release Time for Research (RTR):
IUPUI maintains a robust research enterprise. This funding mechanism allows IUPUI faculty a "buy out" of teaching time to adequately prepare competitive proposals for quality research and scholarly activity. The next RTR application deadline is September 15. Apply to this program through the InfoReady portal. Download the Guidelines and Application. Applications are to be submitted as one pdf file.

IUPUI Arts and Humanities Internal Grant (IAHI):
The IAHI Grant Program supports campus-wide attainment of excellence in research and creative activity in arts and humanities. It is designed to enhance the research and creative activity mission of IUPUI by supporting research projects and scholarly activities that are conducted by arts and humanities faculty. The program is intended to stimulate existing and new research and creative activity and to support faculty in becoming competitive in securing external funding and sponsorship. The next IAHI application deadline is October 1. Apply to this program through the InfoReady portal Download the Guidelines and Application. Applications are to be submitted as one pdf file.

Research Support Funds Grant (RSFG):
The Research Support Funds Grant (RSFG) program is designed to enhance the research mission of IUPUI by supporting research projects and scholarly activities that are sustainable through external funding. The next RSFG application deadline is October 1. Apply to this program through the InfoReady portal. Download the Guidelines and Application. Applications are to be submitted as one pdf file.

International Research Development Fund (IRDF) GRANT:
The IRDF grant was developed to enhance the international research and scholarly activity focus of the IUPUI academic mission. Generally, the IRDF grant serves as venture capital to stimulate additional funding for international research and scholarly activity, which has strong potential to generate indirect cost recovery from extramural sources. The next IRDF application deadline is November 1. Apply to this program through the InfoReady portal. Download the Guidelines and Application. Applications are to be submitted as one pdf file.

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OVCR EVENTS AND WORKSHOPS

Basic Proposal Development
Target Audience: IUPUI and IUPUC faculty, postdoctoral fellows, and graduate students
Thursday, August 31, 2017
11:00am – 12:00pm
University Library, Room 1126

This presentation focuses on basic procedures for developing successful proposals to funding agencies that support research and other scientific/scholarly/educational activities. Topics we will discuss include finding funding opportunities, becoming familiar with funding agencies (e.g., understanding agency missions, application procedures, and review criteria), understanding the basic components of a grant application, basic budget construction (e.g., calculating indirect costs), and the submission process (e.g. routing with IUPUI grants administration office and different agency submission systems). Participants are welcome to bring a lunch to the session.

Click here to register

Focus on the National Science Foundation (NSF)
Target Audiences: IUPUI and IUPUC faculty, postdoctoral fellows, and graduate students in science and engineering
Friday, September 15, 2017
10:00am – 11:30am
University Library, Room 1126

Sponsored by the following divisions of the Office of the Vice Chancellor for Research: Proposal Development Services and the STEM Education Innovation and Research Institute. This session serves as an introduction to preparing grant proposals for submission to the National Science Foundation (NSF). Topics to be discussed include the origins and mission of NSF, budgetary trends at NSF, the organizational structure of NSF, the mechanics of preparing proposals for NSF funding, the proposal review process at NSF, STEM education and workforce development priorities at NSF, and the role of assessment and evaluation in NSF-funded projects. Food and drink are permitted in the session venue.

Click here to register

Focus on the National Institutes of Health (NIH)
Target Audience: IUPUI and IUPUC faculty, postdoctoral fellows, and graduate students
Thursday, October 5, 2017
1:00pm – 3:00pm
University Library, Room 1126

This presentation focuses on grant applications to the National Institutes of Health. Topics we will discuss include becoming familiar with the funding agency (e.g., understanding the agency mission, infrastructure), understanding the different types of mechanisms (e.g., R01, P01, T, K, F), finding funding opportunities (e.g., how to navigate an FOA to identify all elements required for submission), fundamentals of the NIH grants process (e.g., key resources and website), understanding the components of the grant application, basic budget construction, the submission process (e.g., ASSIST & the grants package), and the review process. Participants are welcome to bring a lunch to the session.

Click here to register

Multi-Investigator Complex Proposals Multi-Investigator Complex Proposals
Target Audience: IUPUI and IUPUC senior faculty with previous or current external funding, Signature Center directors
Thursday, October 19, 2017
4:00pm - 5:30pm
University Library, Room 1126

The current funding environment favors large, complex, multi-institutional, multi-investigator projects. However, organizing a successful submission takes a great deal of planning and teamwork. This session will focus on exploring the distinctions between “standard” and “complex” submissions, navigating through issues of building and organizing the research team, intra- and inter-institutional collaboration, and preparing a successful proposal. Participants will also find out what assistance is available from the staff of Proposal Development Services in the Office of the Vice Chancellor for Research. Food and drink are allowed in the session venue. (Limited to 20 registrants.)

Click here to register

Nine Golden Rules to Succeed in Research and Scholarship
Target Audience: faculty
Friday, October 27, 2017
2:30pm – 4:30pm
University Library, Room 1126

This session will reveal the Nine Golden Rules on how to succeed in research and scholarship. It is focused toward new and early career investigators; however, mid-career faculty should find the information of interest as well.

Click here to register

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OTHER EVENTS AND WORKSHOPS

IU School of Nursing hosts Patient Centered Outcomes Research Institute Workshop
The Indiana University School of Nursing is hosting a Patient Centered Outcomes Research Institute (PCORI) Workshop on October 26, 2017 at the University Tower Ballroom. Presentations about the history of PCORI, the review process, priorities, the 10 step process of funding, and community involvement will be given by PCORI funded investigators.

When: October 26, 2017, 9:00 am – 2:30 pm
Where: University Tower, Ball Room

Program:
  • 9:00am History of PCORI, Structure, Review Process, Priorities Robin Newhouse, PhD, RN, NEA-BC, FAAN Dean, Indiana University School of Nursing
  • 10:05am 10 Step Process Dan Mullins, PhD University of Maryland School of Pharmacy
  • 11:30am Lunch
  • 12:15pm Community Involvement Dan Mullins, PhD University of Maryland School of Pharmacy
  • 1:00pm Panel Discussion Susan Rawl, PhD, FAAN Indiana University School of Nursing

    Peter Schwartz, MD, PhD Indiana University School of Medicine

    Michelle Salyers, PhD Indiana University-Purdue University Indianapolis Department of Psychology
  • 2:30pm Wrap up and future steps

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RECENT EXTERNAL FUNDING AWARDS

Grants and Awards – July 2017

PI

Agency

Project Title

School

Department

Total

Ballard, James A

 

INDIANA STATE DEPARTMENT OF HEALTH

 

FY 2018-19 Area Health Education Centers Operating Support

 

MEDICINE

 

FAMILY MEDICINE

 

$4,462,000

 

Dixon, Brian Edward

 

NATIONAL LIBRARY OF MEDICINE

 

The Indiana Training Program in Public & Population Health Informatics

 

PUBLIC HLTH

 

EPIDEMIOLOGY

 

$2,585,297

 

Foroud, Tatiana M

 

NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

 

Dissecting the genetic contributions to fetal alcohol spectrum disorders

 

MEDICINE

 

MEDICAL & MOLECULAR GENETICS

 

$2,584,099

 

Zhang, Jian-Ting

 

NATIONAL CANCER INSTITUTE

 

Molecular targeting the translational control axis in Wnt/?-catenin signaling pathway

 

MEDICINE

 

PHARMACOLOGY & TOXICOLOGY

 

$1,793,515

 

Nho, Kwangsik

 

NATIONAL LIBRARY OF MEDICINE

 

Integrating Neuroimaging, Multi-omics, and Clinical Data in Complex Disease

 

MEDICINE

 

RADIOLOGY & IMAGING SCIENCES

 

$1,733,416

 

Grannis, Shaun J

 

AGENCY FOR HEALTHCARE RESEARCH AND QUALITY

 

Enhancing Patient Matching in Support of Operational Health Information Exchange

 

MEDICINE

 

FAMILY MEDICINE

 

$1,701,413

 

Duman Scheel, Molly

 

U.S. DEPARTMENT OF DEFENSE

 

Effective Interfering RNA Lure and Kill Baited Ovitraps for Biorational Aedes Zika Vector Mosquito Control

 

MEDICINE

 

IUSM-SOUTH BEND

 

$1,088,378

 

Duman Scheel, Molly

 

U.S. DEPARTMENT OF DEFENSE

 

Dual action larvicidal/adulticidal siRNA insecticides for biorational mosquito control

 

MEDICINE

 

IUSM-SOUTH BEND

 

$749,670

 

Sapp, Dona Rae

 

INDIANA CRIMINAL JUSTICE INSTITUTE

 

Traffic Safety

 

PUBLIC & ENVIRONMENTAL AFFAIRS

 

SPEA

 

$350,000

 

Salyers, Michelle Pensec

 

ESKENAZI HEALTH

 

Pilot Study for Adolescents with Depression in Primary Care

 

SCIENCE

 

PSYCHOLOGY

 

$297,045

 

Martin, Douglas K.

 

COGNITIVE MEDICAL SYSTEMS, INC.

 

Clinical Decision Support (CDS) and HL7-Compliant Knowledge Artifacts (KNARTS)

 

MEDICINE

 

GENERAL INTERNAL MEDICINE

 

$222,720

 

Nonweiler-Parr, Jacqueline Marie

 

INDIANA MEDICAL EDUCATION BOARD

 

Indiana Medical Education Board Family Medicine Residency Grant 2017-2018

 

MEDICINE

 

FAMILY MEDICINE - RESIDENTS

 

$117,095

 


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CURRENT EXTERNAL FUNDING OPPORTUNITIES
Funding opportunities in this section include selected current grant announcements from federal agencies for new initiatives and changes to existing programs. Announcements with limited scope are not listed here but instead are sent directly to IUPUI School Deans. For comprehensive coverage of funding opportunities, please use the links below to search online tools.

MELANOMA RESEARCH ALLIANCE
MRA Team Science Awards: Awards for team science are designed to foster a collaborative research process and promote transformational melanoma research advances with the potential for rapid clinical translation. Multidisciplinary teams will receive funding to support projects with the potential to lead to transformative advances in prevention, detection, diagnosis, staging and/or treatment of melanoma. Team Science Awards have a collaborative and multidisciplinary emphasis, involving meaningful collaboration between participants. LOIs must include a description and rationale for the proposed collaboration, the specific role of all PIs and the Young Investigator, and synergistic opportunities derived from the team proposed.
Deadlines: Letter of Intent: Oct. 06, 2017; Application: Jan. 09, 2018
https://www.curemelanoma.org/research/request-for-proposals/

NATIONAL ENDOWMENT FOR THE HUMANITIES
NINDS CREATE Bio Optimization Track for Biologics (UO1): This opportunity supports the optimization of potential therapeutic Biotechnology Products and Biologics (e.g., peptides, proteins, oligonucleotides, gene/cell therapies) for disorders identified under the NINDS mission. This track supports the further characterization and optimization of therapeutic lead(s) that showed promise as a potential therapeutic agent as evidenced by convincing animal proof-of-concept studies. Therefore, at the end of this funding period, successful projects will have delivered and optimized therapeutic candidate with demonstrated bioactivity, stability, manufacturability, bioavailability, in vivo efficacy and should be eligible for entry into the CREATE Bio Development track. The CREATE Bio Development track is a later stage program focused on the development of optimized therapeutic candidates through Investigational New Drug (IND)-enabling studies and submission of an IND package to the Food and Drug Administration (FDA)
Deadline: Feb. 13, 2018.
https://www.grants.gov/web/grants/view-opportunity.html?oppId=296484

Symptom Cluster Characterization in Chronic Conditions (RO1): The purpose of this initiative is to encourage preclinical and clinical research and secondary data analysis on symptom cluster characterization that has potential to inform treatment and interventions that improve functional outcomes and quality of life in patients with chronic conditions. Interdisciplinary collaborations that include nurse scientists are strongly encouraged.

Research objectives include, but are not limited to, the following:
Phenotyping symptom clusters: 1) Assess similarities in symptom cluster phenotypes across chronic conditions, including symptom onset and changes over time; 2) Compare the number and types of symptom clusters across chronic conditions; and 3) Determine phenotypic predictors for the development of a pre-specified symptom cluster in patients with chronic conditions.
Mechanisms of symptom clusters: 1) Investigate the underlying genetic and epigenetic mechanisms for symptom clusters in chronic conditions; 2) Investigate the pathophysiology that may contribute to symptom clusters in chronic conditions; and 3) Develop or adapt computational models or statistical modeling to predict altered biological pathways within a symptom cluster that occur in a chronic condition.
Symptom cluster measurement: 1) Evaluate the use of large data sets and electronic health records to validate measurement or to predict symptom cluster onset in chronic conditions; and 2) Evaluate the validity, reliability and responsiveness of PROMIS measures and common data elements (CDEs) in symptom cluster research pertaining to chronic conditions.

Deadline: Feb. 05, 2018
https://www.grants.gov/custom/viewOppDetails.jsp?oppId=296528

NIAID Research Education Program (R25): The purpose of this opportunity is to encourage basic or clinical research applications that investigate central neural mechanisms of age-related hearing loss in older adults and/or in relevant animal models. This opportunity is driven by the need to address a major gap in our understanding of the central pathways and neural networks that are involved in hearing loss and how these may be altered in the context of the aging brain, as well as how natural aging influences central auditory plasticity.
Deadlines: Letter of Intent: Oct. 08, 2017; Application: Nov. 08, 2017.
https://www.grants.gov/custom/viewOppDetails.jsp?oppId=296344

NATIONAL INSTITUTES OF HEALTH
NINDS CREATE Bio Optimization Track for Biologics (UO1): This opportunity supports the optimization of potential therapeutic Biotechnology Products and Biologics (e.g., peptides, proteins, oligonucleotides, gene/cell therapies) for disorders identified under the NINDS mission. This track supports the further characterization and optimization of therapeutic lead(s) that showed promise as a potential therapeutic agent as evidenced by convincing animal proof-of-concept studies. Therefore, at the end of this funding period, successful projects will have delivered and optimized therapeutic candidate with demonstrated bioactivity, stability, manufacturability, bioavailability, in vivo efficacy and should be eligible for entry into the CREATE Bio Development track. The CREATE Bio Development track is a later stage program focused on the development of optimized therapeutic candidates through Investigational New Drug (IND)-enabling studies and submission of an IND package to the Food and Drug Administration (FDA).
Deadline: Feb. 13, 2018
https://www.grants.gov/web/grants/view-opportunity.html?oppId=296484

Symptom Cluster Characterization in Chronic Conditions (RO1): The purpose of this initiative is to encourage preclinical and clinical research and secondary data analysis on symptom cluster characterization that has potential to inform treatment and interventions that improve functional outcomes and quality of life in patients with chronic conditions. Interdisciplinary collaborations that include nurse scientists are strongly encouraged.

Research objectives include, but are not limited to, the following:
Phenotyping symptom clusters: 1) Assess similarities in symptom cluster phenotypes across chronic conditions, including symptom onset and changes over time; 2) Compare the number and types of symptom clusters across chronic conditions; and 3) Determine phenotypic predictors for the development of a pre-specified symptom cluster in patients with chronic conditions.
Mechanisms of symptom clusters: 1) Investigate the underlying genetic and epigenetic mechanisms for symptom clusters in chronic conditions; 2) Investigate the pathophysiology that may contribute to symptom clusters in chronic conditions; and 3) Develop or adapt computational models or statistical modeling to predict altered biological pathways within a symptom cluster that occur in a chronic condition.
Symptom cluster measurement: 1) Evaluate the use of large data sets and electronic health records to validate measurement or to predict symptom cluster onset in chronic conditions; and 2) Evaluate the validity, reliability and responsiveness of PROMIS measures and common data elements (CDEs) in symptom cluster research pertaining to chronic conditions.

Deadline: Feb. 05, 2018
https://www.grants.gov/custom/viewOppDetails.jsp?oppId=296528

NIAID Research Education Program (R25): The purpose of this opportunity is to encourage basic or clinical research applications that investigate central neural mechanisms of age-related hearing loss in older adults and/or in relevant animal models. This opportunity is driven by the need to address a major gap in our understanding of the central pathways and neural networks that are involved in hearing loss and how these may be altered in the context of the aging brain, as well as how natural aging influences central auditory plasticity.
Deadlines: Letter of Intent: Oct. 08, 2017; Application: Nov. 08, 2017.
https://www.grants.gov/custom/viewOppDetails.jsp?oppId=296344

NATIONAL SCIENCE FOUNDATION
Law & Social Sciences (LSS): The LSS Program considers proposals that address social scientific studies of law and law-like systems of rules. The Program is inherently interdisciplinary and multi-methodological. Successful proposals describe research that advances scientific theory and understanding of the connections between law or legal processes and human behavior. Social scientific studies of law often approach law as dynamic, made in multiple arenas, with the participation of multiple actors. Fields of study include many disciplines, and often address problems including though not limited to: 1) Crime, Violence and Punishment; 2) Economic Issues; 3) Governance; 4) Legal Decision Making, 5) Legal Mobilization and Conceptions of Justice; and 6) Litigation and the Legal Profession.
Deadline: Jan. 17, 2018
https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=504727

Perception, Action & Cognition (PAC): The PAC program funds theoretically motivated research on a wide-range of topic areas focused on typical human behavior. The aim is to enhance the fundamental understanding of perceptual, motor, and cognitive processes and their interactions. Central research topics for consideration by the program include vision, audition, haptics, attention, memory, reasoning, written and spoken language, and motor control. The program welcomes a wide range of perspectives, such as individual differences, symbolic computation, connectionism, ecological, genetics, nonlinear dynamics, and complex systems, and a variety of methodologies including both experimental studies and modeling. The PAC program is open to co-review of proposals submitted to other programs both within the Social, Behavioral, and Economic Sciences Directorate and across other directorates. Proposals may involve clinical populations, animals, brain imaging, or computational modeling, or factors such as emotion and sleep, only if the work has direct impact on our understanding of basic processes underlying human perception, action, or cognition.
Deadline: Feb. 01, 2018
https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=5686

ADVANCE: Increasing the Participation & Advancement of Women in Academic Science & Engineering Careers: The ADVANCE Program will make strategic investments in the development and implementation of institutional transformation strategies and knowledge building activities with the aim of building evidence-based strategies about gender-based institutional transformation and strategies to increase the representation of women in the academic STEM disciplines and environments.

Institutional Transformation (IT): 5-year, comprehensive, institution-wide projects.
IT awards are expected to include innovative and systemic organizational approaches framed with clearly stated and fully integrated theories of change or conceptual frameworks in order to increase the participation and advancement of women in STEM academic careers. IT projects are expected to be designed to achieve the transformation of all departments or schools of STEM fields within the institution and to produce evidence-based replicable strategies.

Project Activities: IT awards provide maximum flexibility to proposing institutions to define and implement systemic organizational approaches to increase the participation of women STEM faculty members; to promote their retention and advancement into the senior and leadership ranks; to address unconscious bias and subtle discrimination that leads to underrepresentation in STEM and leadership positions; to develop activities associated with career-life balance strategies; and to implement the changes necessary to institutionalize those approaches through changes to institutional policies, procedures and practices.

Institutional Transformation Catalyst: up to 3-year projects.
The IT Catalyst track is meant to develop and implement unique strategies - either adapted from those found effective in the IT track or ones designed to be responsive to the unique environments of eligible institutions - and evaluate the effectiveness of those strategies. The target institutions are those that provide unique contexts (1) to learn from adapting effective strategies from other ADVANCE projects and/or (2) to learn from developing a coherent thematic set of activities meant to address a documented institutional problem related to gender equity in STEM. IT Catalyst programs should aim to transform all departments or schools of STEM fields within the institution and to produce evidence-based replicable strategies.

Project activities should involve all STEM sciences and be designed to catalyze change on the campus that will promote gender equity in STEM, recruitment and retention activities to promote enhanced representation and advancement of women on that campus, or significant change in the policy environment for faculty.

Partnerships for Learning and Adaptation Networks (PLAN): up to 5-year projects.
PLAN projects can focus on all STEM disciplines, several disciplines, or only one discipline. Projects that have national systemic impact across a discipline or a set of related disciplines are particularly encouraged. Proposals that involve activities targeted toward special populations of women faculty are encouraged, in which case, the project description must include current institutional or disciplinary data on this group, disaggregated by multiple characteristics (e.g., race, ethnicity, disability status, sexual orientation), as appropriate, in addition to gender.

PLAN projects but there should have 1 main activity for adaptation/implementation into different institutional contexts. Previous or current funding from ADVANCE is not a prerequisite for submitting a PLAN proposal. The portion of the project focused on knowledge building must be led and conceptualized by individuals with appropriate expertise in learning, policy analysis, and/or evaluation depending upon what is being adapted/implemented through a network.

Deadlines: Letter of Intent: Aug. 09, 2019; Full Proposal: Sept. 13, 2019.
https://www.nsf.gov/pubs/2016/nsf16594/nsf16594.htm?WT.mc_id=USNSF_25&WT.mc_ev=click

NOTE: : All faculty, researchers, and scientists on continuing contracts at IU interested in applying for Department of Defense funding are eligible for assistance by the consulting firm--Cornerstone Government Affairs-arranged by the Vice President for Research. Those interested in securing assistance from Cornerstone must submit a 2 page summary of their research project and a CV or biosketch to the VP for Research Office at vpr@iu.edu. Prior to submission, the IUPUI Office of the Vice Chancellor for Research is offering assistance with the 2 page summaries. For more information, contact Steven Chin schin@iupui.edu.

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